Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors
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چکیده
منابع مشابه
Epigenetic inactivation of CHFR in human tumors.
Cell-cycle checkpoints controlling the orderly progression through mitosis are frequently disrupted in human cancers. One such checkpoint, entry into metaphase, is regulated by the CHFR gene encoding a protein possessing forkhead-associated and RING finger domains as well as ubiquitin-ligase activity. Although defects in this checkpoint have been described, the molecular basis and prevalence of...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2007
ISSN: 1460-2180,0143-3334
DOI: 10.1093/carcin/bgm178